1,10-Phenanthroline platinum(II) complex: a simple molecule for efficient G-quadruplex stabilization.
نویسندگان
چکیده
Two simple complexes [Pt(phen)(2)](PF(6))(2) and [Pt(bpy)(2)](PF(6))(2) exhibit high stabilization potential for G-quadruplex DNA with [Pt(phen)(2)](PF(6))(2) possessing higher capability due to its greater planarity.
منابع مشابه
Synthesis, antitumor activity and G-quadruplex DNA/ct-DNA binding property of a cationic platinum(II) complex of 2-(4-nitro)-imidazo-[5,6-f][1,10]-phenanthroline
A cationic platinum(II) complex (1), [Pt(4-NOIP)(en)]·Cl2 (4-NOIP = 2-(4-nitro)-imidazo-[5,6-f][1,10]-phenanthroline, en = 1,2-ethylenediamine), has been synthesized and characterized by IR, UV-vis, ESI-MS and element analysis. The interaction of complex (1) with ct-DNA and human telomeric G-quadruplex DNA [Htel-21] has been investigated by circular dichroism absorption and UV–vis absorption ti...
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Two polypyridyl copper(II) complexes, [Cu(phen)(phen-dione)Cl]Cl (1) and [Cu(bpy) (phen-dione)Cl]Cl (2), (where Phen =1,10-phenanthroline, bpy =2,2'-bipyridine and Phen-dione = 1,10-phenanthroline-5,6-dione), were used as efficient catalysts for the oxidation of benzyl alcohol to benzaldehyde. The effects of various parameters such as reaction temperature, reaction time, etc. were studied. The ...
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ورودعنوان ژورنال:
- Dalton transactions
دوره 39 31 شماره
صفحات -
تاریخ انتشار 2010